Researchers Uncover Gut Microbiota Shifts Linked to COVID and Probiotics

New York: The '13th Gut Microbiota for Health World Summit,' held recently in Washington, DC, highlighted groundbreaking research translating gut microbiome science into clinical practice.

One key study presented at the summit revealed how COVID-19 affects gut microbiota in children, similar to observations in adults. Researchers found that children who had recovered from COVID-19 exhibited reduced levels of beneficial gut bacteria such as Lacticaseibacillus and Bifidobacterium, compared to those who were never infected. These bacteria are known to support gut health and reduce inflammation. Additionally, children experiencing lingering post-COVID symptoms showed distinct bacterial profiles, higher inflammation markers, and weakened gut barrier function. Future studies aim to explore targeted therapies focusing on the gut microbiome to manage persistent post-COVID conditions.

Another study at the summit examined the presence of S100B, a calcium-binding protein, in common foods. Researchers analysed 35 plant-based and 23 dairy-based food items, discovering that almost half contained S100B. This protein may influence gut bacteria composition and contribute to gut health, potentially offering benefits in managing conditions like inflammatory bowel disease (IBD). Experts suggested that these findings could pave the way for incorporating S100B into dietary supplements and nutraceutical products to promote gut health.

In addition, a meta-analysis involving 10 clinical studies with over 2,300 patients highlighted the benefits of probiotics in post-colonoscopy recovery. Results indicated that probiotics significantly reduced abdominal pain, bloating, and vomiting after the procedure. However, there was no notable improvement in symptoms such as nausea, constipation, gas, or diarrhoea. The findings suggest that probiotics may enhance patient comfort and recovery, possibly encouraging more people to undergo colonoscopy, an essential screening tool.

The summit, jointly organized by the American Gastroenterological Association (AGA) and the European Society of Neurogastroenterology and Motility (ESNM), brought together leading clinicians, researchers, nutritionists, and dietitians to discuss the latest advancements in gut microbiome research and its practical applications.