In this video, Dr. Anantha Padmanabha dicusses Herpes zoster, caused by the varicella-zoster virus, targeting primarily older adults, particularly those aged 50 and above, as well as individuals with compromised immune systems and presenting as a painful rash along specific nerve pathways. With a keen focus on diagnosis methods, he outlines the key indicators used by healthcare professionals to identify shingles, emphasizing the importance of prompt recognition and treatment. He also sheds light on the potential complications, including the debilitating post-herpetic neuralgia, which can linger long after the rash has subsided and can significantly impact the quality of life for those affected. Lastly. Dr. Padmanabha talks about the shingles vaccine—a vital tool in prevention and elaborates on the two-dose regimen, spaced over several months while underscoring its proven efficacy in reducing the risk of shingles development, as well as alleviating symptom severity in breakthrough cases.