Genetic Defences Against Alcohol Linked To Heart Disease And Mental Health, Study Finds
The findings suggest a broader impact of these genetic defenses.
New research reveals a twist on genes that protect against heavy drinking. While these genes offer a shield against alcoholism, they may also be linked to other health conditions.
Scientists conducted a large-scale DNA analysis, examining over 3 million genetic records. They focused on variations in genetic code known as SNPs, which have previously been tied to both lower alcohol consumption and a reduced risk of alcohol use disorder (AUD).
These "lightweight genes" sometimes trigger unpleasant reactions to alcohol, like nausea, acting as a built-in deterrent to overconsumption.
However, the study suggests these genes might also play a role in other health areas. The researchers found connections to conditions like heart disease and mental health issues, although the exact nature of these links requires further investigation.
The study by the research group centered at the University of California San Diego School of Medicine has drilled deep into a dataset of over 3 million individuals, and it was recently published in the Lancet eBioMedicine.
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"The people who have the minor allele variant of the SNP convert ethanol to acetaldehyde very rapidly. And that causes a lot of negative effects," said the corresponding author and associate professor at the UC San Diego School of Medicine Department of Psychiatry. She went on to say that the resulting nausea eclipses any pleasurable effects of alcohol-think of a bad hangover that sets in almost immediately.
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She explained that the study used genetic data to broadly classify individuals as being European, Latin American, and African American.
A study has unveiled significant connections between gene variants influencing alcohol use and a range of non-alcohol-related health conditions.
New research reveals a twist on genes that protect against heavy drinking. While these genes offer a shield against alcoholism, they may also be linked to other health conditions.
Scientists conducted a large-scale DNA analysis, examining over 3 million genetic records. They focused on variations in genetic code known as SNPs, which have previously been tied to both lower alcohol consumption and a reduced risk of alcohol use disorder (AUD).
These "lightweight genes" sometimes trigger unpleasant reactions to alcohol, like nausea, acting as a built-in deterrent to overconsumption.
However, the study suggests these genes might also play a role in other health areas. The researchers found connections to conditions like heart disease and mental health issues, although the exact nature of these links requires further investigation.
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Stating that nothing has yet been done about suppliers of pharmaceutical drugs in the Capital being not paid for medicines worth Rs 90 crore for over six months — due to which the medicine supply is being affected — Delhi’s special secretary (health department) has asked the Directorate General of Health Services (DGHS) and the Central Procurement Agency (CPA) to take an action in the matter.
Taking cognisance of a related report published by The Indian Express on April 16, SK Jain, special secretary (Health and Family Welfare), directed the two departments to process all the files related to the payment of medicine suppliers at the earliest. In a letter issued to the DGHS and the CPA on April 18, Jain said that the Secretary (H&FW) discussed the matter with the DGHS about 45 days ago, where it was directed that all the files received for the release of the payment must be processed soon, except the ones blacklisted; however, no action has been taken yet.
